GW 6471 from Cayman Chemical

Product Specs
ItemGW 6471
CompanyCayman Chemical
Price Pricing Info Supplier Page View Company Product Page
Catalog Number11697
Quantity10 mg
FormatA crystalline solid
Research AreaEndocrinology & Metabolism, Hormones & Receptors, PPARs
Molecular Weight619.7
Purity≥98%

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Selective activation of PPARα maintains thermogenic capacity of beige adipocytesiScienceJuly 21, 2023Gentaro Egusa, Haruya Ohno, Gaku Nagano, Junji Sagawa, Hiroko Shinjo, Yutaro Yamamoto, Natsumi Himeno, Yoshimi Morita, Akinori Kanai, Ryuta Baba, et al.Tokyo, Japan",N/A Bezafibrate,Wako,Cat# 022-16091 GW9578,SantaCruz,Cat# SC-221703 GW6471,Cayman,Cat# 11697 Recombinant Proteinase K Solution,Invitrogen,Cat# AM2546 RNaseA,NIPPON GENE,Cat# 313-01461 "RNase,DNase

(2) Adipolin protects against renal injury via PPARα-dependent reduction of inflammasome activationiScienceMay 19, 2023Fang L, Ohashi K, Hayakawa S, Ogawa H, Otaka N, Kawanishi H, Takikawa T, Ozaki Y, Takahara K, Tatsumi M, et al.proteins","Chemicals, peptides, and recombinant proteins" ,, MCC950,Adipogen,AG-CR1-3615 GW6471,Cayman,11697 SB431542,Cayman,13031 LY294002,Cell Signaling Technology,#9901 Recombinant angiotensin II protein,Sigma-Aldrich,A9525 ,, Critical

(3) Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complexCell reportsOctober 18, 2022Xie L, Yuan Y, Xu S, Lu S, Gu J, Wang Y, Wang Y, Zhang X, Chen S, Li J, et al.GW9578 (10 μM, Cayman Chemical Company, USA; 10011211), GW6471 (10 μM, Cayman Chemical Company, USA; 11697), BCS (100 μM, 200 μM, Sigma-Aldrich, USA; B1125), TM (toluene, 10 μM, Sigma-Aldrich, USA; 323446),

(4) FGF1Î”HBS delays the progression of diabetic nephropathy in late-stage type 2 diabetes mouse model by alleviating renal inflammation, fibrosis, and apoptosisBiochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAugust 1, 2022Qian Lin, Oscar Chen, John P. Wise, HongXue Shi, Kupper A. Wintergerst, Lu Cai, Yi Tanstudies [16,21]. The peroxisome proliferator-activated receptor (PPARα) inhibitor (GW6471, Cat No: 11697, Cayman Chemical) was dissolved in dimethyl sulfoxide (DMSO). After serum starvation for 24 h, BUMPT

(5) Lipid Messenger Phosphatidylinositol-4,5-Bisphosphate Is Increased by Both PPARα Activators and Inhibitors: Relevance for Intestinal Cell DifferentiationBiologyJune 30, 2022Cizkova K, Koubova K, Tauber Z.cat. no. 10005368), WY-14643 (Sigma-Aldrich; cat. no. C7081), and GW6471 (Cayman chemicals, cat. no. 11697) were prepared by dissolving in DMSO. The cells were seeded in 96-well cultivation plates (TPP, cat.

(6) Oleoylethanolamide as a New Therapeutic Strategy to Alleviate Doxorubicin-Induced CardiotoxicityFrontiers in PharmacologyApril 20, 2022Yeyu Qin, Jing Xie, Ruihe Zheng, Yuhang Li, Haixia Wangfenofibrate (Cat. #F129682), capsazepine (Cat. #C126558) was purchased from Aladdin. GW6471 (Cat. # 11697) and nonivamide (Cat. # 25328) was purchased from Cayman chemical. Animals and Treatments The animal experiments

(7) Metabolic flexibility maintains proliferation and migration of FGFR signaling–deficient lymphatic endothelial cellsJournal of Biological ChemistryOctober 1, 2021Hongyuan Song, Jie Zhu, Ping Li, Fei Han, Longhou Fang, Pengchun Yupurchased from Selleckchem (#S6539). The PPARα antagonist GW6471 was purchased from Cayman Chemical (#11697). The PPARγ antagonist GW9662 was purchased from Sigma (#M6191). 2-DG was ordered from Sigma (#D8375).

(8) When Activator and Inhibitor of PPARα Do the Same: Consequence for Differentiation of Human Intestinal CellsBiomedicinesSeptember 17, 2021Cizkova K, Foltynkova T, Hanyk J, Kamencak Z, Tauber Z.Louis, USA, cat. no. C7081) and PPARα inhibitor (GW6471 (Cayman Chemicals, Michigan, USA, cat. no. 11697)) in the following concentrations: 25 μM and 150 μM (HT-29) or 200 μM (Caco2) fenofibrate, 25 μM and

(9) Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in AstrocytesInternational Journal of Molecular SciencesDecember 16, 2020Dmitry V. Chistyakov, Alina A. Astakhova, Sergei V. Goriainov, Marina G. SergeevaReagents Lipopolysaccharide (cat.no. L2630) were from (Sigma-Aldrich, St. Louis, MO, USA), GW6471 (cat.no. 11697), GW9662 (cat.no. 70785), GSK0660 (cat.no. 15272), GW501516 (cat.no. 10004272) and fenofibrate (cat.no.

(10) A novel selective PPARα modulator, pemafibrate promotes ischemia-induced revascularization through the eNOS-dependent mechanismsPLOS ONEJune 25, 2020Hiroshi Kawanishi, Koji Ohashi, Hayato Ogawa, Naoya Otaka, Tomonobu Takikawa, Lixin Fang, Yuta Ozaki, Mikito Takefuji, Toyoaki Murohara, Noriyuki Ouchi(L-NAME) was purchased from Sigma (St. Louis, MO) (N5751). GW6471 was purchased from Cayman Chemical (11697). Recombinant human FGF21 protein was purchased from R&D system (2539-FG025). Plasma FGF21 levels were

(11) IL-15 Mediates Mitochondrial Activity through a PPARδ-Dependent-PPARα-Independent Mechanism in Skeletal Muscle CellsPPAR ResearchSeptember 21, 2016Shantaé M. Thornton, James E. Krolopp, Marcia J. Abbotthorse serum (#H1270), and insulin (#I9278). Recombinant IL-15 was from GenScript (#Z03309-50) and GW-6471 (#11697) PPAR Research and GSK-3787 (#15219) were obtained from Cayman Chemicals. Trizol (#15596), SYBR green

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GW 6471 from Cayman Chemical

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Cayman Chemical

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GW 6471 from Cayman Chemical

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